efficacy of adenosine for acute treatment of supraventricular tachycardia in infants and children
نویسندگان
چکیده
background: this study was done to assess the efficacy and adverse effects of the different doses of adenosine in the pediatric age group with respect to multiple patient variables. methods: over a period of 1 year, 86 occasions of supraventricular tachycardia (svt) were treated with adenosine in 81 infants and children aged between 18 days and 12 years (median of 1.3 years, sd=3). adenosine efficacy was evaluated in terms of the patients’ demographics, svt rate, electrocardiogram characteristics, and route of drug administration . results: the dose of 50μg/kg was effective only in 24% of the svt cases, and the additional doses of 100μg/kg, 150μg/kg, and 200μg/kg were effective in another 29% of the cases. the drug efficacy was higher in the infants than that in the older children. there were no predictors other than age for the estimation of the efficacy of the drug. conclusion: our findings showed that the current recommended doses of adenosine are ineffective in the vast majority of children and infants with svt. no patient-related factor other than age seems to affect the efficacy of the drug .
منابع مشابه
Efficacy and safety of adenosine in the treatment of supraventricular tachycardia in infants and children.
One hundred and seventeen episodes of supraventricular tachycardia in 50 children, including 28 infants, were treated with intravenous adenosine. Adenosine was prepared in a sterile solution of 0.9% saline (1 mg/ml) and given in incremental doses of 0.05 mg/kg every two minutes to a maximum of 0.25 mg/kg. Ninety of the 117 episodes were terminated. This included 88 of the 102 episodes of juncti...
متن کاملOptimal dose of adenosine effective for supraventricular tachycardia in children.
OBJECTIVE To determine the optimal adenosine dose effective in supraventricular tachycardia (SVT) and underlying conditions affecting the effective dose in children. STUDY DESIGN Experimental study. PLACE AND DURATION OF STUDY Department of Cardiology, The Children's Hospital and Institute of Child Health, Lahore, from July 2008 to June 2011. METHODOLOGY All children presenting with SVT w...
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چکیده ندارد.
15 صفحه اولAdenosine administration in supraventricular tachycardia
The ECG during symptoms was strongly suggestive of typical atrial flutter. After adenosine administration, the heart rate slowed for a few seconds because of 3:1 atrioventricular (AV) conduction, but it then changed to 1:1 conduction response (Fig. 1). This was associated with haemodynamic instability, which required electrocardioversion. Although adenosine administration is usually innocuous, ...
متن کاملGuidelines and adenosine dosing in supraventricular tachycardia.
This retrospective review of present practice of administration of adenosine by paediatricians shows that current guidelines recommend starting doses that are effective in only 9% of infants and children.
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عنوان ژورنال:
the journal of tehran university heart centerجلد ۳، شماره ۳، صفحات ۱۵۷-۱۶۲
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